AquilaBiopharmaceuticals Inc .'s proprietary adjuvant called Stimulonis extracted from the bark of a tree ( Quillaja saponaria ) found in South America.
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The key components of ISCOMs are the Quillaja saponins, which are derived from the bark of the Chilean soap-bark tree Quillaja saponaria Molina.
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In particular, the saponins from " Quillaja saponaria " are used in veterinary vaccines as adjuvant ( e . g ., foot-and-mouth disease vaccines, helping to enhance the immune response ).